2LKX
NMR structure of the homeodomain of Pitx2 in complex with a TAATCC DNA binding site
Replaces: 1YZ8Summary for 2LKX
Entry DOI | 10.2210/pdb2lkx/pdb |
NMR Information | BMRB: 18015 |
Descriptor | Pituitary homeobox 3, DNA (5'-D(*GP*CP*TP*CP*TP*AP*AP*TP*CP*CP*CP*CP*G)-3'), DNA (5'-D(*CP*GP*GP*GP*GP*AP*TP*TP*AP*GP*AP*GP*C)-3') (3 entities in total) |
Functional Keywords | transcription-dna complex, transcription/dna |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus (By similarity): O75364 |
Total number of polymer chains | 3 |
Total formula weight | 16430.71 |
Authors | Baird-Titus, J.M.,Doerdelmann, T.,Chaney, B.A.,Clark-Baldwin, K.,Dave, V.,Ma, J. (deposition date: 2011-10-21, release date: 2012-05-02, Last modification date: 2024-05-01) |
Primary citation | Chaney, B.A.,Clark-Baldwin, K.,Dave, V.,Ma, J.,Rance, M. Solution structure of the K50 class homeodomain PITX2 bound to DNA and implications for mutations that cause Rieger syndrome Biochemistry, 44:7497-7511, 2005 Cited by PubMed: 15895993DOI: 10.1021/bi0473253 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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