Solution structure of the chimeric Af1503 HAMP- EnvZ DHp homodimer; A219F variant

Summary for 2LFS

Related3ZRX 3ZRW 3ZRV 2LFR
DescriptorUncharacterized protein, Osmolarity sensor protein envZ chimera (1 entity in total)
Functional Keywordstransmembrane signaling, hamp domain, histidine kinase, gearbox model, transferase
Biological sourceArchaeoglobus fulgidus, Shigella flexneri
Cellular locationCell inner membrane; Multi-pass membrane protein (By similarity) P0AEJ5
Total number of polymer chains2
Total molecular weight26007.55
Coles, M.,Ferris, H.U.,Hulko, M.,Martin, J.,Lupas, A.N. (deposition date: 2011-07-10, release date: 2011-08-24, Last modification date: 2012-02-01)
Primary citation
Ferris, H.U.,Dunin-Horkawicz, S.,Hornig, N.,Hulko, M.,Martin, J.,Schultz, J.E.,Zeth, K.,Lupas, A.N.,Coles, M.
Mechanism of regulation of receptor histidine kinases.
Structure, 20:56-66, 2012
PubMed: 22244755 (PDB entries with the same primary citation)
DOI: 10.1016/j.str.2011.11.014
MImport into Mendeley
Experimental method
NMR Information

Structure validation

ClashscoreRamachandran outliersSidechain outliers500MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures