2LFG

Solution structure of the human prolactin receptor ecd domain d2

Summary for 2LFG

• Entry DOI: 10.2210/pdb2lfg/pdb
• Related: 1RW5 3D48 3EW3 3MZG 3NPZ
• NMR Information: BMRB: 17752
• Descriptor: Prolactin receptor (1 entity in total)
• Functional Keywords: extracellular domain, cytokine receptor, hormone receptor
• Biological source: Homo sapiens (human)
• Cellular location: Membrane; Single-pass type I membrane protein. Isoform 7: Secreted: P16471
• Total number of polymer chains: 1
• Total formula weight: 13343.34

Authors

Dagil, R.,Knudsen, M.J.,Kragelund, B.B.,O'Shea, C.,Teilum, K. (deposition date: 2011-06-30, release date: 2012-02-15, Last modification date: 2023-06-14)

• Primary citation: Dagil, R.,Knudsen, M.J.,Olsen, J.G.,O'Shea, C.,Franzmann, M.,Goffin, V.,Teilum, K.,Breinholt, J.,Kragelund, B.B.; The WSXWS Motif in Cytokine Receptors Is a Molecular Switch Involved in Receptor Activation: Insight from Structures of the Prolactin Receptor; Structure, 20:270-282, 2012; PubMed: 22325776; DOI: 10.1016/j.str.2011.12.010

Experimental method

SOLUTION NMR