2L27
NMR Structure of the ECD1 of CRF-R1 in complex with a peptide agonist
Summary for 2L27
Entry DOI | 10.2210/pdb2l27/pdb |
Related | 2JNC 2JND |
Descriptor | Corticotropin-releasing factor receptor 1, peptide agonist (2 entities in total) |
Functional Keywords | crf, ecd1, agonist, family b1, alpha helical crf, membrane protein, peptide binding protein |
Biological source | Homo sapiens (human) |
Cellular location | Cell membrane; Multi-pass membrane protein: P34998 |
Total number of polymer chains | 2 |
Total formula weight | 13560.15 |
Authors | Grace, C.R.R.,Perrin, M.H.,Gulyas, J.R.R.,Rivier, J.E.,Vale, W.W.,Riek, R.R. (deposition date: 2010-08-12, release date: 2010-09-01, Last modification date: 2017-03-01) |
Primary citation | Grace, C.R.,Perrin, M.H.,Gulyas, J.,Rivier, J.E.,Vale, W.W.,Riek, R. NMR structure of the first extracellular domain of corticotropin-releasing factor receptor 1 (ECD1-CRF-R1) complexed with a high affinity agonist. J.Biol.Chem., 285:38580-38589, 2010 Cited by PubMed: 20843795DOI: 10.1074/jbc.M110.121897 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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