2KWF
The structure of E-protein activation domain 1 bound to the KIX domain of CBP/p300 elucidates leukemia induction by E2A-PBX1
Summary for 2KWF
Entry DOI | 10.2210/pdb2kwf/pdb |
NMR Information | BMRB: 16851 |
Descriptor | CREB-binding protein, Transcription factor 4 (2 entities in total) |
Functional Keywords | transcription, transferase |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm: Q92793 Nucleus (Probable): P15884 |
Total number of polymer chains | 2 |
Total formula weight | 12375.04 |
Authors | Denis, C.M.,Chitayat, S.,Plevin, M.J.,Liu, S.,Spencer, H.L.,Ikura, M.,LeBrun, D.P.,Smith, S.P. (deposition date: 2010-04-08, release date: 2011-07-20, Last modification date: 2024-05-01) |
Primary citation | Denis, C.M.,Chitayat, S.,Plevin, M.J.,Liu, S.,Spencer, H.L.,Ikura, M.,LeBrun, D.P.,Smith, S.P. The structure of E-protein activation domain 1 bound to the KIX domain of CBP/p300 elucidates leukemia induction by E2A-PBX1 To be Published, |
Experimental method | SOLUTION NMR |
Structure validation
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