2KWF
The structure of E-protein activation domain 1 bound to the KIX domain of CBP/p300 elucidates leukemia induction by E2A-PBX1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | CREB-binding protein | polymer | 87 | 10353.9 | 1 | UniProt (Q92793) Pfam (PF02172) | Homo sapiens (human) | |
| 2 | B (B) | Transcription factor 4 | polymer | 19 | 2021.2 | 1 | UniProt (P15884) | Homo sapiens (human) | TCF-4, Immunoglobulin transcription factor 2, ITF-2, SL3-3 enhancer factor 2, SEF-2, Class B basic helix-loop-helix protein 19, bHLHb19 |
Sequence modifications
B: 90 - 106 (UniProt: P15884)
| PDB | External Database | Details |
|---|---|---|
| Gly 88 | - | expression tag |
| Ser 89 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 12375.0 | |
| All* | Total formula weight | 12375.0 |
