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2KWF

The structure of E-protein activation domain 1 bound to the KIX domain of CBP/p300 elucidates leukemia induction by E2A-PBX1

Functional Information from GO Data
ChainGOidnamespacecontents
A0003712molecular_functiontranscription coregulator activity
A0004402molecular_functionhistone acetyltransferase activity
A0006355biological_processregulation of DNA-templated transcription
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsMOD_RES: Asymmetric dimethylarginine => ECO:0000250|UniProtKB:P45481
ChainResidueDetails
AARG15
AARG39

site_idSWS_FT_FI2
Number of Residues1
DetailsMOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:P45481
ChainResidueDetails
ALYS71

222926

PDB entries from 2024-07-24

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