2KS9

Solution conformation of substance P in water complexed with NK1R

Summary for 2KS9

• Entry DOI: 10.2210/pdb2ks9/pdb
• Related: 2KSA 2KSB
• NMR Information: BMRB: 16660,20115
• Descriptor: Substance-P receptor, Substance P (2 entities in total)
• Functional Keywords: substance p, water, autodock, nk1, neuropeptide receptor-neuropeptide complex, neuropeptide receptor/neuropeptide
• Biological source: Homo sapiens (human); More
• Cellular location: Cell membrane; Multi-pass membrane protein: P25103; Secreted: P20366
• Total number of polymer chains: 2
• Total formula weight: 43030.47

Authors

Gayen, A.,Mukhopadhyay, C. (deposition date: 2009-12-31, release date: 2010-11-03, Last modification date: 2011-07-13)

• Primary citation: Gayen, A.,Goswami, S.K.,Mukhopadhyay, C.; NMR evidence of GM1-induced conformational change of Substance P using isotropic bicelles; Biochim.Biophys.Acta, 2010; PubMed: 20937248; DOI: 10.1016/j.bbamem.2010.09.023

Experimental method

SOLUTION NMR