2KGK
Solution structure of Bacillus anthracis dihydrofolate reductase
Summary for 2KGK
Entry DOI | 10.2210/pdb2kgk/pdb |
NMR Information | BMRB: 16822 |
Descriptor | Dihydrofolate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 5-[3-(2,5-dimethoxyphenyl)prop-1-yn-1-yl]-6-ethylpyrimidine-2,4-diamine (3 entities in total) |
Functional Keywords | dhfr, oxidoreductase |
Biological source | Bacillus anthracis (anthrax,anthrax bacterium) |
Total number of polymer chains | 1 |
Total formula weight | 21552.07 |
Authors | Deshmukh, L.,Vinogradova, O.,Beierlein, J.M.,Frey, K.M.,Anderson, A.C. (deposition date: 2009-03-12, release date: 2009-05-12, Last modification date: 2024-05-22) |
Primary citation | Beierlein, J.M.,Deshmukh, L.,Frey, K.M.,Vinogradova, O.,Anderson, A.C. The solution structure of Bacillus anthracis dihydrofolate reductase yields insight into the analysis of structure-activity relationships for novel inhibitors. Biochemistry, 48:4100-4108, 2009 Cited by PubMed: 19323450DOI: 10.1021/bi802319w PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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