2KFB

The structure of the cataract causing P23T mutant of human gamma-D crystallin

Summary for 2KFB

• Entry DOI: 10.2210/pdb2kfb/pdb
• NMR Information: BMRB: 16173
• Descriptor: Gamma-crystallin D (1 entity in total)
• Functional Keywords: crystallin, cataract, protein, lens, disease mutation, eye lens protein, oxidation, sensory transduction, vision, structural protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 21856.35

Authors

Jung, J.,Byeon, I.L.,Wang, Y.,King, J.,Gronenborn, A.M. (deposition date: 2009-02-12, release date: 2009-07-28, Last modification date: 2024-05-22)

• Primary citation: Jung, J.,Byeon, I.J.,Wang, Y.,King, J.,Gronenborn, A.M.; The structure of the cataract-causing P23T mutant of human gammaD-crystallin exhibits distinctive local conformational and dynamic changes.; Biochemistry, 48:2597-2609, 2009; PubMed: 19216553; DOI: 10.1021/bi802292q

Experimental method

SOLUTION NMR