2KFB

The structure of the cataract causing P23T mutant of human gamma-D crystallin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Gamma-crystallin D	polymer	182	21856.3	1	UniProt (P07320) Pfam (PF00030) In PDB	Homo sapiens (human)	Gamma-D-crystallin, Gamma-crystallin 4

Sequence modifications

A: 2 - 174 (UniProt: P07320)

PDB	External Database	Details
Met -7	-	expression tag
Lys -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
Gln 1	-	expression tag
Thr 24	Pro 24	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	21856.3
All*	Total formula weight	21856.3

*Water molecules are not included.