2KFB
The structure of the cataract causing P23T mutant of human gamma-D crystallin
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0002088 | biological_process | lens development in camera-type eye |
| A | 0005212 | molecular_function | structural constituent of eye lens |
| A | 0005515 | molecular_function | protein binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0007601 | biological_process | visual perception |
| A | 0034614 | biological_process | cellular response to reactive oxygen species |
| A | 0070306 | biological_process | lens fiber cell differentiation |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 38 |
| Details | Domain: {"description":"Beta/gamma crystallin 'Greek key' 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00028","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 42 |
| Details | Domain: {"description":"Beta/gamma crystallin 'Greek key' 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00028","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 40 |
| Details | Domain: {"description":"Beta/gamma crystallin 'Greek key' 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00028","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 42 |
| Details | Domain: {"description":"Beta/gamma crystallin 'Greek key' 4","evidences":[{"source":"PROSITE-ProRule","id":"PRU00028","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 3 |
| Details | Region: {"description":"Connecting peptide"} |
| Chain | Residue | Details |
