2K9Y

EphA2 dimeric structure in the lipidic bicelle at pH 5.0

Summary for 2K9Y

• Entry DOI: 10.2210/pdb2k9y/pdb
• Related: 2k1k 2k1l
• NMR Information: BMRB: 16005
• Descriptor: Ephrin type-A receptor 2 (2 entities in total)
• Functional Keywords: receptor tyrosine kinase, membrane protein, dimeric transmembrane domain, ephrin receptor, atp-binding, glycoprotein, kinase, membrane, nucleotide-binding, phosphoprotein, polymorphism, receptor, transferase, transmembrane, tyrosine-protein kinase
• Biological source: Homo sapiens (Human)
• Cellular location: Cell membrane; Single-pass type I membrane protein: P29317
• Total number of polymer chains: 2
• Total formula weight: 8566.10

Authors

Mayzel, M.L.,Bocharov, E.V.,Volynsky, P.E.,Arseniev, A.S. (deposition date: 2008-10-27, release date: 2009-08-11, Last modification date: 2022-03-16)

• Primary citation: Bocharov, E.V.,Mayzel, M.L.,Volynsky, P.E.,Mineev, K.S.,Tkach, E.N.,Ermolyuk, Y.S.,Schulga, A.A.,Efremov, R.G.,Arseniev, A.S.; Left-Handed Dimer of EphA2 Transmembrane Domain: Helix Packing Diversity among Receptor Tyrosine Kinases; Biophys.J., 98:881-889, 2010; PubMed: 20197042; DOI: 10.1016/j.bpj.2009.11.008

Experimental method

SOLUTION NMR