2K1K

NMR structures of dimeric transmembrane domain of the receptor tyrosine kinase EphA1 in lipid bicelles at pH 4.3

Summary for 2K1K

• Entry DOI: 10.2210/pdb2k1k/pdb
• Related: 2k1l
• NMR Information: BMRB: 15728
• Descriptor: Ephrin type-A receptor 1 (1 entity in total)
• Functional Keywords: epha1, receptor tyrosine kinase, dimeric transmembrane domain, atp-binding, glycoprotein, nucleotide-binding, phosphoprotein, polymorphism, transferase, tyrosine-protein kinase, signaling protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 7789.40

Authors

Mayzel, M.L.,Bocharov, E.V.,Arseniev, A.S.,Goncharuk, M.V. (deposition date: 2008-03-06, release date: 2008-09-09, Last modification date: 2023-06-14)

• Primary citation: Bocharov, E.V.,Mayzel, M.L.,Volynsky, P.E.,Goncharuk, M.V.,Ermolyuk, Y.S.,Schulga, A.A.,Artemenko, E.O.,Efremov, R.G.,Arseniev, A.S.; Spatial Structure and pH-dependent Conformational Diversity of Dimeric Transmembrane Domain of the Receptor Tyrosine Kinase EphA1; J.Biol.Chem., 283:29385-29395, 2008; PubMed: 18728013; DOI: 10.1074/jbc.M803089200

Experimental method

SOLUTION NMR