2JZW

How the HIV-1 nucleocapsid protein binds and destabilises the (-)primer binding site during reverse transcription

2JZW の概要

• エントリーDOI: 10.2210/pdb2jzw/pdb
• 分子名称: HIV-1 nucleocapsid protein NCp7(12-55), DNA (5'-D(*DGP*DTP*DCP*DCP*DCP*DTP*DGP*DTP*DTP*DCP*DGP*DGP*DGP*DC)-3'), ZINC ION (3 entities in total)
• 機能のキーワード: human immunodeficiency virus type 1 (hiv-1), nuclear magnetic resonance (nmr), nucleocapsid protein (ncp7), primer binding site (pbs), exchange, viral protein-dna complex, viral protein/dna
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 9417.39

構造登録者

Bourbigot, S.,Ramalanjaona, N.,Salgado, G.F.J.,Mely, Y.,Roques, B.P.,Bouaziz, S.,Morellet, N. (登録日: 2008-01-21, 公開日: 2009-01-13, 最終更新日: 2022-03-16)

• 主引用文献: Bourbigot, S.,Ramalanjaona, N.,Boudier, C.,Salgado, G.F.,Roques, B.P.,Mely, Y.,Bouaziz, S.,Morellet, N.; How the HIV-1 nucleocapsid protein binds and destabilises the (-)primer binding site during reverse transcription.; J.Mol.Biol., 383:1112-1128, 2008; PubMed: 18773912; DOI: 10.1016/j.jmb.2008.08.046

実験手法

SOLUTION NMR