2JJO

Structure of cytochrome P450 EryK in complex with its natural substrate erD

2JJO の概要

• エントリーDOI: 10.2210/pdb2jjo/pdb
• 関連するPDBエントリー: 2JJN 2JJP 2VRU 2VRV 2WIO
• 分子名称: CYTOCHROME P450 113A1, PROTOPORPHYRIN IX CONTAINING FE, Erythromycin D, ... (4 entities in total)
• 機能のキーワード: iron, heme, monooxygenase, metal-binding, antibiotic biosynthesis, tie-rod mechanism of action, oxidoreductase, substrate specificity
• 由来する生物種: SACCHAROPOLYSPORA ERYTHRAEA
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 46667.42

構造登録者

Savino, C.,Sciara, G.,Miele, A.E.,Kendrew, S.G.,Vallone, B. (登録日: 2008-04-15, 公開日: 2009-07-14, 最終更新日: 2023-12-13)

• 主引用文献: Savino, C.,Montemiglio, L.C.,Sciara, G.,Miele, A.E.,Kendrew, S.G.,Jemth, P.,Gianni, S.,Vallone, B.; Investigating the Structural Plasticity of a Cytochrome P450: Three-Dimensional Structures of P450 Eryk and Binding to its Physiological Substrate.; J.Biol.Chem., 284:29170-, 2009; PubMed: 19625248; DOI: 10.1074/JBC.M109.003590

実験手法

X-RAY DIFFRACTION (1.99 Å)