2JE4
Atomic-resolution crystal structure of chemically-synthesized HIV-1 protease in complex with JG-365
Summary for 2JE4
| Entry DOI | 10.2210/pdb2je4/pdb |
| Related PRD ID | PRD_000228 |
| Descriptor | PROTEASE, INHIBITOR MOLECULE JG365, ACETATE ION, ... (6 entities in total) |
| Functional Keywords | protease, hydrolase, high resolution, aspartyl protease, human immunodeficiency virus 1, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
| Biological source | HUMAN IMMUNODEFICIENCY VIRUS 1 More |
| Total number of polymer chains | 3 |
| Total formula weight | 23329.08 |
| Authors | Malito, E.,Johnson, E.C.B.,Tang, W.J. (deposition date: 2007-01-15, release date: 2007-08-28, Last modification date: 2023-12-13) |
| Primary citation | Johnson, E.C.B.,Malito, E.,Shen, Y.,Rich, D.,Tang, W.J.,Kent, S.B. Modular Total Chemical Synthesis of a Human Immunodeficiency Virus Type 1 Protease. J.Am.Chem.Soc., 129:11480-, 2007 Cited by PubMed: 17705484DOI: 10.1021/JA072870N PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.07 Å) |
Structure validation
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