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2JD0

X-ray structure of mutant 1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXR, Rv2870c, from Mycobacterium tuberculosis, in complex with NADPH

Summary for 2JD0
Entry DOI10.2210/pdb2jd0/pdb
Related2C82 2JCV 2JCX 2JCY 2JCZ 2JD1 2JD2
Descriptor1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SULFATE ION, ... (4 entities in total)
Functional Keywordsoxidoreductase, doxp/mep pathway, isoprene biosynthesis, 1-deoxy-d-xylulose 5-phosphate reductoisomerase, nadp, rv2870c, metal-binding
Biological sourceMYCOBACTERIUM TUBERCULOSIS
Total number of polymer chains2
Total formula weight84431.61
Authors
Henriksson, L.M.,Unge, T.,Jones, T.A.,Mowbray, S.L. (deposition date: 2007-01-04, release date: 2007-05-08, Last modification date: 2023-12-13)
Primary citationHenriksson, L.M.,Unge, T.,Carlsson, J.,Aqvist, J.,Mowbray, S.L.,Jones, T.A.
Structures of Mycobacterium Tuberculosis 1-Deoxy-D- Xylulose-5-Phosphate Reductoisomerase Provide New Insights Into Catalysis.
J.Biol.Chem., 282:19905-, 2007
Cited by
PubMed: 17491006
DOI: 10.1074/JBC.M701935200
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.3 Å)
Structure validation

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