2JCV
X-ray structure of 1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXR, Rv2870c, from Mycobacterium tuberculosis, in complex with fosmidomycin and NADPH
Summary for 2JCV
Entry DOI | 10.2210/pdb2jcv/pdb |
Related | 2C82 2JCX 2JCY 2JCZ 2JD0 2JD1 2JD2 |
Descriptor | 1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE, 3-[FORMYL(HYDROXY)AMINO]PROPYLPHOSPHONIC ACID, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (5 entities in total) |
Functional Keywords | oxidoreductase, doxp/mep pathway, isoprene biosynthesis, 1-deoxy-d-xylulose 5-phosphate reductoisomerase, nadp, rv2870c, metal-binding |
Biological source | MYCOBACTERIUM TUBERCULOSIS |
Total number of polymer chains | 2 |
Total formula weight | 85268.01 |
Authors | Henriksson, L.M.,Unge, T.,Jones, T.A.,Mowbray, S.L. (deposition date: 2007-01-04, release date: 2007-05-08, Last modification date: 2023-12-13) |
Primary citation | Henriksson, L.M.,Unge, T.,Carlsson, J.,Aqvist, J.,Mowbray, S.L.,Jones, T.A. Structures of Mycobacterium Tuberculosis 1-Deoxy-D- Xylulose-5-Phosphate Reductoisomerase Provide New Insights Into Catalysis. J.Biol.Chem., 282:19905-, 2007 Cited by PubMed: 17491006DOI: 10.1074/JBC.M701935200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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