2JAW

Crystal structure of D41N variant of human mitochondrial 5'(3')- deoxyribonucleotidase (mdN) in complex with 5-bromovinyldeoxyuridine 5'-monophosphate

2JAW の概要

• エントリーDOI: 10.2210/pdb2jaw/pdb
• 関連するPDBエントリー: 1MH9 1Q91 1Q92 1Z4I 1Z4J 1Z4K 1Z4L 1Z4M 1Z4P 1Z4Q 2JAU
• 分子名称: 5'(3')-DEOXYRIBONUCLEOTIDASE, (E)-5-(2-BROMOVINYL)-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, MAGNESIUM ION, ... (4 entities in total)
• 機能のキーワード: transit peptide, nucleotide-binding, mitochondrial, metal-binding, alfa beta fold, nucleotide- binding, nucleotide metabolism, hydrolase, magnesium, mitochondrion
• 由来する生物種: HOMO SAPIENS (HUMAN)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 23301.86

構造登録者

Wallden, K.,Ruzzenente, B.,Bianchi, V.,Nordlund, P. (登録日: 2006-11-30, 公開日: 2007-11-20, 最終更新日: 2024-05-08)

• 主引用文献: Wallden, K.,Rinaldo-Matthis, A.,Ruzzenente, B.,Rampazzo, C.,Bianchi, V.,Nordlund, P.; Crystal Structures of Human and Murine Deoxyribonucleotidases: Insights Into Recognition of Substrates and Nucleotide Analogues.; Biochemistry, 46:13809-, 2007; PubMed: 17985935; DOI: 10.1021/BI7014794

実験手法

X-RAY DIFFRACTION (1.95 Å)