2JAJ

DDAH1 complexed with L-257

Summary for 2JAJ

• Entry DOI: 10.2210/pdb2jaj/pdb
• Related: 1H70 2JAI
• Descriptor: NG, NG-DIMETHYLARGININE DIMETHYLAMINOHYDROLASE 1, N~5~-{IMINO[(2-METHOXYETHYL)AMINO]METHYL}-L-ORNITHINE (3 entities in total)
• Functional Keywords: ddah, hydrolase, nitric oxide synthase inhibitor
• Biological source: HOMO SAPIENS (HUMAN)
• Total number of polymer chains: 2
• Total formula weight: 63438.89

Authors

Murray-Rust, J.,O'Hara, B.P.,Rossiter, S.,Leiper, J.M.,Vallance, P.,McDonald, N.Q. (deposition date: 2006-11-29, release date: 2007-02-13, Last modification date: 2019-05-08)

• Primary citation: Leiper, J.,Nandi, M.,Torondel, B.,Murray-Rust, J.,Malaki, M.,O'Hara, B.,Rossiter, S.,Anthony, S.,Madhani, M.,Selwood, D.,Smith, C.,Wojciak-Stothard, B.,Rudiger, A.,Stidwill, R.,McDonald, N.Q.,Vallance, P.; Disruption of methylarginine metabolism impairs vascular homeostasis.; Nat. Med., 13:198-203, 2007; PubMed: 17273169; DOI: 10.1038/nm1543

Experimental method

X-RAY DIFFRACTION (2 Å)