2J9K

Atomic-resolution Crystal Structure of Chemically-Synthesized HIV-1 Protease Complexed with Inhibitor MVT-101

Summary for 2J9K

Entry DOI	10.2210/pdb2j9k/pdb
Related	2J9J
Related PRD ID	PRD_000398
Descriptor	PROTEASE, N-{(2S)-2-[(N-acetyl-L-threonyl-L-isoleucyl)amino]hexyl}-L-norleucyl-L-glutaminyl-N~5~-[amino(iminio)methyl]-L-ornithinamide, SULFATE ION, ... (6 entities in total)
Functional Keywords	protease, hydrolase-hydrolase inhibitor complex, aspartyl protease, human immunodeficiency virus 1, hydrolase/hydrolase inhibitor
Biological source	HUMAN IMMUNODEFICIENCY VIRUS 1
Total number of polymer chains	2
Total formula weight	23223.99
Authors	Malito, E.,Shen, Y.,Johnson, E.C.B.,Tang, W.J. (deposition date: 2006-11-11, release date: 2007-08-28, Last modification date: 2023-12-13)
Primary citation	Johnson, E.C.B.,Malito, E.,Shen, Y.,Pentelute, B.,Rich, D.,Florian, J.,Tang, W.J.,Kent, S.B.H. Insights from Atomic-Resolution X-Ray Structures of Chemically Synthesized HIV-1 Protease in Complex with Inhibitors. J.Mol.Biol., 373:573-, 2007 Cited by PubMed: 17869270 DOI: 10.1016/J.JMB.2007.07.054 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.2 Å)

Structure validation