2J3N

X-ray structure of human thioredoxin reductase 1

Summary for 2J3N

Entry DOI	10.2210/pdb2j3n/pdb
Related	1W1C 1W1E 2CFY
Descriptor	THIOREDOXIN REDUCTASE 1, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (5 entities in total)
Functional Keywords	fad, nadp, human, selenium, cytoplasm, flavoprotein, redox regulation, electron transport, oxidoreductase, selenocysteine, phosphorylation, pyridine nucleotide dependent disulfide reductase, redox-active center
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Cytoplasm . Isoform 4: Cytoplasm. Isoform 5: Cytoplasm: Q16881
Total number of polymer chains	6
Total formula weight	351415.80
Authors	Fritz-Wolf, K.,Urig, S.,Becker, K. (deposition date: 2006-08-22, release date: 2007-07-03, Last modification date: 2023-12-13)
Primary citation	Fritz-Wolf, K.,Urig, S.,Becker, K. The Structure of Human Thioredoxin Reductase 1 Provides Insights Into C-Terminal Rearrangements During Catalysis. J.Mol.Biol., 370:116-, 2007 Cited by PubMed: 17512005 DOI: 10.1016/J.JMB.2007.04.044 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation