2IZZ

Crystal structure of human pyrroline-5-carboxylate reductase

Summary for 2IZZ

• Entry DOI: 10.2210/pdb2izz/pdb
• Descriptor: PYRROLINE-5-CARBOXYLATE REDUCTASE 1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, 1,2-ETHANEDIOL, ... (4 entities in total)
• Functional Keywords: amino-acid biosynthesis, nadp, oxidoreductase, proline biosynthesis
• Biological source: HOMO SAPIENS (HUMAN)
• Cellular location: Mitochondrion : P32322
• Total number of polymer chains: 5
• Total formula weight: 173967.38

Authors

Pike, A.C.W.,Guo, K.,Kavanagh, K.,Pilka, E.S.,Berridge, G.,Colebrook, S.,Bray, J.,Salah, E.,Savitsky, P.,Papagrigoriou, E.,Turnbull, A.P.,von Delft, F.,Arrowsmith, C.,Edwards, A.,Weigelt, J.,Sundstrom, M.,Oppermann, U. (deposition date: 2006-07-31, release date: 2006-08-01, Last modification date: 2023-12-13)

• Primary citation: Pike, A.C.W.,Guo, K.,Kavanagh, K.,Pilka, E.S.,Berridge, G.,Colebrook, S.,Bray, J.,Salah, E.,Savitsky, P.,Papagrigoriou, E.,Turnbull, A.P.,von Delft, F.,Arrowsmith, C.,Edwards, A.,Weigelt, J.,Sundstrom, M.,Oppermann, U.; Crystal Structure of Human Pyrroline-5-Carboxylate Reductase; To be Published,

Experimental method

X-RAY DIFFRACTION (1.95 Å)