2IYK
Crystal structure of the UPF2-interacting domain of nonsense mediated mRNA decay factor UPF1
Summary for 2IYK
Entry DOI | 10.2210/pdb2iyk/pdb |
Descriptor | REGULATOR OF NONSENSE TRANSCRIPTS 1, ZINC ION (2 entities in total) |
Functional Keywords | nmd, zinc, upf1, helicase, hydrolase, zinc-finger, nucleotide-binding, surveillance complex, nonsense-mediated mrna decay, alternative splicing, nonsense mediated mrna decay, atp-binding, metal-binding, phosphorylation |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Cytoplasm: Q92900 |
Total number of polymer chains | 2 |
Total formula weight | 36824.39 |
Authors | Kadlec, J.,Guilligay, D.,Ravelli, R.B.,Cusack, S. (deposition date: 2006-07-18, release date: 2006-08-30, Last modification date: 2024-05-08) |
Primary citation | Kadlec, J.,Guilligay, D.,Ravelli, R.B.,Cusack, S. Crystal Structure of the Upf2-Interacting Domain of Nonsense-Mediated Mrna Decay Factor Upf1. RNA, 12:1817-, 2006 Cited by PubMed: 16931876DOI: 10.1261/RNA.177606 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.95 Å) |
Structure validation
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