2IYK

Crystal structure of the UPF2-interacting domain of nonsense mediated mRNA decay factor UPF1

2IYK の概要

• エントリーDOI: 10.2210/pdb2iyk/pdb
• 分子名称: REGULATOR OF NONSENSE TRANSCRIPTS 1, ZINC ION (2 entities in total)
• 機能のキーワード: nmd, zinc, upf1, helicase, hydrolase, zinc-finger, nucleotide-binding, surveillance complex, nonsense-mediated mrna decay, alternative splicing, nonsense mediated mrna decay, atp-binding, metal-binding, phosphorylation
• 由来する生物種: HOMO SAPIENS (HUMAN)
• 細胞内の位置: Cytoplasm: Q92900
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 36824.39

構造登録者

Kadlec, J.,Guilligay, D.,Ravelli, R.B.,Cusack, S. (登録日: 2006-07-18, 公開日: 2006-08-30, 最終更新日: 2024-05-08)

• 主引用文献: Kadlec, J.,Guilligay, D.,Ravelli, R.B.,Cusack, S.; Crystal Structure of the Upf2-Interacting Domain of Nonsense-Mediated Mrna Decay Factor Upf1.; RNA, 12:1817-, 2006; PubMed: 16931876; DOI: 10.1261/RNA.177606

実験手法

X-RAY DIFFRACTION (2.95 Å)