2IYF

The crystal structure of macrolide glycosyltransferases: A blueprint for antibiotic engineering

2IYF の概要

• エントリーDOI: 10.2210/pdb2iyf/pdb
• 分子名称: OLEANDOMYCIN GLYCOSYLTRANSFERASE, ERYTHROMYCIN A, URIDINE-5'-DIPHOSPHATE, ... (5 entities in total)
• 機能のキーワード: antibiotic resistance, glycosylation, glycosyltransferase, enzyme, macrolide, transferase, carbohydrate
• 由来する生物種: STREPTOMYCES ANTIBIOTICUS
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 93084.50

構造登録者

Bolam, D.N.,Roberts, S.M.,Proctor, M.R.,Turkenburg, J.P.,Dodson, E.J.,Martinez-Fleites, C.,Yang, M.,Davis, B.G.,Davies, G.J.,Gilbert, H.J. (登録日: 2006-07-17, 公開日: 2007-03-27, 最終更新日: 2024-05-08)

• 主引用文献: Bolam, D.N.,Roberts, S.M.,Proctor, M.R.,Turkenburg, J.P.,Dodson, E.J.,Martinez-Fleites, C.,Yang, M.,Davis, B.G.,Davies, G.J.,Gilbert, H.J.; The Crystal Structure of Two Macrolide Glycosyltransferases Provides a Blueprint for Host Cell Antibiotic Immunity.; Proc.Natl.Acad.Sci.USA, 104:5336-, 2007; PubMed: 17376874; DOI: 10.1073/PNAS.0607897104

実験手法

X-RAY DIFFRACTION (1.7 Å)