2IVJ

Isopenicillin N Synthase From Aspergillus Nidulans (Anaerobic Ac- cyclopropylglycine Fe Complex)

2IVJ の概要

• エントリーDOI: 10.2210/pdb2ivj/pdb
• 関連するPDBエントリー: 1BK0 1BLZ 1HB1 1HB2 1HB3 1HB4 1IPS 1OBN 1OC1 1ODM 1ODN 1QIQ 1QJE 1QJF 1UZW 1W03 1W04 1W05 1W06 1W3V 1W3X 2BJS 2BU9 2IVI
• 分子名称: ISOPENICILLIN N SYNTHETASE, D-(L-A-AMINOADIPOYL)-L-CYSTEINYL-D-CYCLOPROPYLGLYCINE, SULFATE ION, ... (5 entities in total)
• 機能のキーワード: antbiotic biosynthesis, antibiotic biosynthesis, iron, oxygenase, vitamin c, metal-binding, penicillin biosynthesis, oxidoreductase, b-lactam antibiotic
• 由来する生物種: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 38173.22

構造登録者

Howard-Jones, A.R.,Elkins, J.M.,Clifton, I.J.,Roach, P.L.,Adlington, R.M.,Baldwin, J.E.,Rutledge, P.J. (登録日: 2006-06-13, 公開日: 2007-04-10, 最終更新日: 2024-05-08)

• 主引用文献: Howard-Jones, A.R.,Elkins, J.M.,Clifton, I.J.,Roach, P.L.,Adlington, R.M.,Baldwin, J.E.,Rutledge, P.J.; Interactions of Isopenicillin N Synthase with Cyclopropyl-Containing Substrate Analogues Reveal New Mechanistic Insight.; Biochemistry, 46:4755-, 2007; PubMed: 17397141; DOI: 10.1021/BI062314Q

実験手法

X-RAY DIFFRACTION (1.46 Å)