2IPI

Crystal Structure of Aclacinomycin Oxidoreductase

Summary for 2IPI

Entry DOI	10.2210/pdb2ipi/pdb
Descriptor	Aclacinomycin oxidoreductase (AknOx), METHYL (2S,4R)-2-ETHYL-2,5,7-TRIHYDROXY-6,11-DIOXO-4-{[2,3,6-TRIDEOXY-4-O-{2,6-DIDEOXY-4-O-[(2S,6S)-6-METHYL-5-OXOTETRAHYDRO-2H-PYRAN-2-YL]-ALPHA-D-LYXO-HEXOPYRANOSYL}-3-(DIMETHYLAMINO)-D-RIBO-HEXOPYRANOSYL]OXY}-1,2,3,4,6,11-HEXAHYDROTETRACENE-1-CARBOXYLATE, FLAVIN-ADENINE DINUCLEOTIDE, ... (4 entities in total)
Functional Keywords	anthracycline, aclacinomycin, oxidoreductase, flavoenzyme, twinning, mad
Biological source	Streptomyces galilaeus
Total number of polymer chains	4
Total formula weight	232841.08
Authors	Sultana, A.,Kursula, I.,Schneider, G.,Alexeev, I.,Niemi, J.,Mantsala, P. (deposition date: 2006-10-12, release date: 2007-01-23, Last modification date: 2011-07-13)
Primary citation	Sultana, A.,Alexeev, I.,Kursula, I.,Mantsala, P.,Niemi, J.,Schneider, G. Structure determination by multiwavelength anomalous diffraction of aclacinomycin oxidoreductase: indications of multidomain pseudomerohedral twinning. Acta Crystallogr.,Sect.D, 63:149-159, 2007 Cited by PubMed: 17242508 DOI: 10.1107/S0907444906044271 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.65 Å)

Structure validation