2IPI
Crystal Structure of Aclacinomycin Oxidoreductase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Aclacinomycin oxidoreductase (AknOx) | polymer | 521 | 57221.8 | 4 | UniProt (Q0PCD7) Pfam (PF01565) Pfam (PF08031) | Streptomyces galilaeus | |
| 2 | E (A) | METHYL (2S,4R)-2-ETHYL-2,5,7-TRIHYDROXY-6,11-DIOXO-4-{[2,3,6-TRIDEOXY-4-O-{2,6-DIDEOXY-4-O-[(2S,6S)-6-METHYL-5-OXOTETRAHYDRO-2H -PYRAN-2-YL]-ALPHA-D-LYXO-HEXOPYRANOSYL}-3-(DIMETHYLAMINO)-D-RIBO-HEXOPYRANOSYL]OXY}-1,2,3,4,6,11-HEXAHYDROTETRACENE-1-C ARBOXYLATE | non-polymer | 811.9 | 1 | Chemie (AKY) | |||
| 3 | F, G, H, I (A, B, C, D) | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 4 | Chemie (FAD) | |||
| 4 | J, K, L, M (A, B, C, D) | water | water | 18.0 | 1009 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 502 (UniProt: Q0PCD7)
| PDB | External Database | Details |
|---|---|---|
| Met -18 | - | initiating methionine |
| Ala -17 | - | cloning artifact |
| His -16 | - | expression tag |
| His -15 | - | expression tag |
| His -14 | - | expression tag |
| His -13 | - | expression tag |
| His -12 | - | expression tag |
| His -11 | - | expression tag |
| His -10 | - | expression tag |
| Arg -9 | - | cloning artifact |
| Ser -8 | - | cloning artifact |
| Ala -7 | - | cloning artifact |
| Ala -6 | - | cloning artifact |
| Gly -5 | - | cloning artifact |
| Thr -4 | - | cloning artifact |
| Ile -3 | - | cloning artifact |
| Trp -2 | - | cloning artifact |
| Glu -1 | - | cloning artifact |
| Phe 0 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 228887.0 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 3954.1 | |
| All* | Total formula weight | 232841.1 |
