2IPI
Crystal Structure of Aclacinomycin Oxidoreductase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Aclacinomycin oxidoreductase (AknOx) | polymer | 521 | 57221.8 | 4 | UniProt (Q0PCD7) | Streptomyces galilaeus | |
| 2 | E (A) | METHYL (2S,4R)-2-ETHYL-2,5,7-TRIHYDROXY-6,11-DIOXO-4-{[2,3,6-TRIDEOXY-4-O-{2,6-DIDEOXY-4-O-[(2S,6S)-6-METHYL-5-OXOTETRAHYDRO-2H -PYRAN-2-YL]-ALPHA-D-LYXO-HEXOPYRANOSYL}-3-(DIMETHYLAMINO)-D-RIBO-HEXOPYRANOSYL]OXY}-1,2,3,4,6,11-HEXAHYDROTETRACENE-1-C ARBOXYLATE | non-polymer | 811.9 | 1 | Chemie (AKY) PubChem (154943) PubChem (16218982) PubChem (16401516) PubChem (24868278) PubChem (451415) PubChem (46783797) PubChem (49866630) PubChem (58076467) PubChem (58783100) PubChem (68028763) PubChem (68022659) PubChem (176518839) PubChem (2008) PubChem (42474) PubChem (6712061) PubChem (152688) PubChem (308141) PubChem (90474433) PubChem (71571506) PubChem (13224415) PubChem (118439199) PubChem (118332683) PubChem (6713097) PubChem (124226146) PubChem (124327196) PubChem (124328804) PubChem (124747801) PubChem (124716841) PubChem (124747799) PubChem (124894851) PubChem (125463062) PubChem (125463063) PubChem (123134262) PubChem (124226147) PubChem (124716839) PubChem (124716840) PubChem (124747800) PubChem (124894850) PubChem (138107521) PubChem (125463060) PubChem (125463061) PubChem (13224414) PubChem (13224422) PubChem (129721008) PubChem (140341747) PubChem (146159245) PubChem (161185366) PubChem (163074497) PubChem (163285913) PubChem (163074498) | |||
| 3 | F, G, H, I (A, B, C, D) | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 4 | Chemie (FAD) | |||
| 4 | J, K, L, M (A, B, C, D) | water | water | 18.0 | 1009 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 502 (UniProt: Q0PCD7)
| PDB | External Database | Details |
|---|---|---|
| Met -18 | - | initiating methionine |
| Ala -17 | - | cloning artifact |
| His -16 | - | expression tag |
| His -15 | - | expression tag |
| His -14 | - | expression tag |
| His -13 | - | expression tag |
| His -12 | - | expression tag |
| His -11 | - | expression tag |
| His -10 | - | expression tag |
| Arg -9 | - | cloning artifact |
| Ser -8 | - | cloning artifact |
| Ala -7 | - | cloning artifact |
| Ala -6 | - | cloning artifact |
| Gly -5 | - | cloning artifact |
| Thr -4 | - | cloning artifact |
| Ile -3 | - | cloning artifact |
| Trp -2 | - | cloning artifact |
| Glu -1 | - | cloning artifact |
| Phe 0 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 228887.0 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 3954.1 | |
| All* | Total formula weight | 232841.1 |
