2IOC
The crystal structure of TREX1 explains the 3' nucleotide specificity and reveals a polyproline II helix for protein partenring
Summary for 2IOC
Entry DOI | 10.2210/pdb2ioc/pdb |
Descriptor | Three prime repair exonuclease 1, MANGANESE (II) ION, 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, ... (4 entities in total) |
Functional Keywords | proline helix, nucleotide complex, dnaq family, hydrolase |
Biological source | Mus musculus (house mouse) |
Cellular location | Nucleus: Q91XB0 |
Total number of polymer chains | 2 |
Total formula weight | 53717.70 |
Authors | de Silva, U.,Hollis, T. (deposition date: 2006-10-10, release date: 2007-02-20, Last modification date: 2018-02-14) |
Primary citation | de Silva, U.,Choudhury, S.,Bailey, S.L.,Harvey, S.,Perrino, F.W.,Hollis, T. The Crystal Structure of TREX1 Explains the 3' Nucleotide Specificity and Reveals a Polyproline II Helix for Protein Partnering. J.Biol.Chem., 282:10537-10543, 2007 Cited by PubMed: 17293595DOI: 10.1074/jbc.M700039200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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