2IOC
The crystal structure of TREX1 explains the 3' nucleotide specificity and reveals a polyproline II helix for protein partenring
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | B, A | Three prime repair exonuclease 1 | polymer | 242 | 26417.8 | 2 | UniProt (Q91XB0) In PDB | Mus musculus (house mouse) | 3'-5' exonuclease TREX1 |
| 2 | B, A | MANGANESE (II) ION | non-polymer | 54.9 | 4 | Chemie (MN) | |||
| 3 | B, A | 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE | non-polymer | 331.2 | 2 | Chemie (D5M) | |||
| 4 | water | water | 18.0 | 249 | Chemie (HOH) |
Sequence modifications
B, A: 1 - 242 (UniProt: Q91XB0)
| PDB | External Database | Details |
|---|---|---|
| Mse 11 | Met 11 | MODIFIED RESIDUE |
| Mse 232 | Met 232 | MODIFIED RESIDUE |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 52835.5 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 882.2 | |
| All* | Total formula weight | 53717.7 |
