2IGY
Achiral, Cheap and Potent Inhibitors of Plasmepsins II
Summary for 2IGY
Entry DOI | 10.2210/pdb2igy/pdb |
Related | 2BJU 2IGX |
Descriptor | Plasmepsin-2, N-[1-(3-METHYLBUTYL)PIPERIDIN-4-YL]-N-{4-[METHYL(PYRIDIN-4-YL)AMINO]BENZYL}-4-PENTYLBENZAMIDE (3 entities in total) |
Functional Keywords | achiral inhibitor, hydrolase |
Biological source | Plasmodium falciparum (malaria parasite P. falciparum) |
Cellular location | Vacuole: P46925 |
Total number of polymer chains | 2 |
Total formula weight | 74989.03 |
Authors | Prade, L. (deposition date: 2006-09-25, release date: 2006-11-28, Last modification date: 2011-07-13) |
Primary citation | Boss, C.,Corminboeuf, O.,Grisostomi, C.,Meyer, S.,Jones, A.F.,Prade, L.,Binkert, C.,Fischli, W.,Weller, T.,Bur, D. Achiral, Cheap, and Potent Inhibitors of Plasmepsins I, II, and IV. Chemmedchem, 1:1341-1345, 2006 Cited by PubMed: 17091526DOI: 10.1002/cmdc.200600223 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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