2IGY
Achiral, Cheap and Potent Inhibitors of Plasmepsins II
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Plasmepsin-2 | polymer | 329 | 36953.7 | 2 | UniProt (P46925) Pfam (PF00026) | Plasmodium falciparum (malaria parasite P. falciparum) | Aspartic hemoglobinase II, PFAPD |
| 2 | C, D (A, B) | N-[1-(3-METHYLBUTYL)PIPERIDIN-4-YL]-N-{4-[METHYL(PYRIDIN-4-YL)AMINO]BENZYL}-4-PENTYLBENZAMIDE | non-polymer | 540.8 | 2 | Chemie (A2T) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 74 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 73907.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1081.6 | |
| All* | Total formula weight | 74989.0 |
