2IFG
Structure of the extracellular segment of human TRKA in complex with nerve growth factor
Summary for 2IFG
Entry DOI | 10.2210/pdb2ifg/pdb |
Descriptor | High affinity nerve growth factor receptor, Beta-nerve growth factor, 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total) |
Functional Keywords | trk, trka, ngf, nerve growth factor, receptor-ligand complex, transferase |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 109542.64 |
Authors | He, X.,Garcia, K.C. (deposition date: 2006-09-20, release date: 2007-02-13, Last modification date: 2023-08-30) |
Primary citation | Wehrman, T.,He, X.,Raab, B.,Dukipatti, A.,Blau, H.,Garcia, K.C. Structural and mechanistic insights into nerve growth factor interactions with the TrkA and p75 receptors. Neuron, 53:25-38, 2007 Cited by PubMed: 17196528DOI: 10.1016/j.neuron.2006.09.034 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.4 Å) |
Structure validation
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