2IBS
Crystal structure of the adenine-specific DNA methyltransferase M.TaqI complexed with the cofactor analog AETA and a 10 bp DNA containing 2-aminopurine at the target position
Summary for 2IBS
Entry DOI | 10.2210/pdb2ibs/pdb |
Related | 1AQI 1AQJ 1G38 2ADM 2IBT |
Descriptor | 5'-D(*GP*TP*TP*CP*GP*(2PR)P*TP*GP*TP*C)-3', 5'-D(*GP*AP*CP*AP*TP*CP*GP*(6MA)P*AP*C)-3', Modification methylase TaqI, ... (5 entities in total) |
Functional Keywords | dna, dna methyltransferase, 2-aminopurine, base flipping, nucleotide flipping, transferase-dna complex, transferase/dna |
Biological source | Thermus aquaticus More |
Total number of polymer chains | 6 |
Total formula weight | 108721.23 |
Authors | Pljevaljcic, G.,Lenz, T.,Scheidig, A.J.,Weinhold, E. (deposition date: 2006-09-12, release date: 2007-05-29, Last modification date: 2023-10-25) |
Primary citation | Lenz, T.,Bonnist, E.Y.M.,Pljevaljcic, G.,Neely, R.K.,Dryden, D.T.F.,Scheidig, A.J.,Jones, A.C.,Weinhold, E. 2-Aminopurine Flipped into the Active Site of the Adenine-Specific DNA Methyltransferase M.TaqI: Crystal Structures and Time-Resolved Fluorescence J.Am.Chem.Soc., 129:6240-6248, 2007 Cited by PubMed: 17455934DOI: 10.1021/ja069366n PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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