Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003676 | molecular_function | nucleic acid binding |
A | 0003677 | molecular_function | DNA binding |
A | 0006304 | biological_process | DNA modification |
A | 0008168 | molecular_function | methyltransferase activity |
A | 0009007 | molecular_function | site-specific DNA-methyltransferase (adenine-specific) activity |
A | 0009307 | biological_process | DNA restriction-modification system |
A | 0032259 | biological_process | methylation |
D | 0003676 | molecular_function | nucleic acid binding |
D | 0003677 | molecular_function | DNA binding |
D | 0006304 | biological_process | DNA modification |
D | 0008168 | molecular_function | methyltransferase activity |
D | 0009007 | molecular_function | site-specific DNA-methyltransferase (adenine-specific) activity |
D | 0009307 | biological_process | DNA restriction-modification system |
D | 0032259 | biological_process | methylation |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 14 |
Details | BINDING SITE FOR RESIDUE NEA A 1001 |
Chain | Residue |
A | VAL21 |
A | HOH1088 |
A | HOH1114 |
A | HOH1115 |
A | HOH1135 |
A | HOH1246 |
A | ALA47 |
A | GLU71 |
A | ILE72 |
A | ALA88 |
A | ASP89 |
A | PHE90 |
A | ASN105 |
A | PRO107 |
site_id | AC2 |
Number of Residues | 15 |
Details | BINDING SITE FOR RESIDUE NEA D 1002 |
Chain | Residue |
D | VAL21 |
D | ALA47 |
D | GLU71 |
D | ILE72 |
D | ASP73 |
D | ALA88 |
D | ASP89 |
D | PHE90 |
D | ASN105 |
D | PRO107 |
D | PHE146 |
D | HOH1074 |
D | HOH1170 |
D | HOH1186 |
D | HOH1198 |
Functional Information from PROSITE/UniProt
site_id | PS00092 |
Number of Residues | 7 |
Details | N6_MTASE N-6 Adenine-specific DNA methylases signature. ILGNPPY |
Chain | Residue | Details |
A | ILE102-TYR108 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | THR23 | |
D | PRO107 | |
A | GLU45 | |
A | GLU71 | |
A | ASP89 | |
A | PRO107 | |
D | THR23 | |
D | GLU45 | |
D | GLU71 | |
D | ASP89 | |
site_id | SWS_FT_FI2 |
Number of Residues | 4 |
Details | SITE: Important for catalytic activity => ECO:0007744|PDB:2ADM |
Chain | Residue | Details |
A | ASN105 | |
A | TYR108 | |
D | ASN105 | |
D | TYR108 | |
site_id | SWS_FT_FI3 |
Number of Residues | 2 |
Details | SITE: Important for catalytic activity; via amide nitrogen => ECO:0007744|PDB:2ADM |
Chain | Residue | Details |
A | PRO106 | |
D | PRO106 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 2adm |
Chain | Residue | Details |
A | PRO106 | |
A | ASN105 | |
A | TYR108 | |
site_id | CSA2 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 2adm |
Chain | Residue | Details |
D | PRO106 | |
D | ASN105 | |
D | TYR108 | |
site_id | MCSA1 |
Number of Residues | 4 |
Details | M-CSA 46 |
Chain | Residue | Details |
A | ASN105 | activator, electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor |
A | PRO106 | activator, electrostatic stabiliser, hydrogen bond acceptor |
A | TYR108 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor |
A | PHE196 | steric role |
site_id | MCSA2 |
Number of Residues | 4 |
Details | M-CSA 46 |
Chain | Residue | Details |
D | ASN105 | activator, electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor |
D | PRO106 | activator, electrostatic stabiliser, hydrogen bond acceptor |
D | TYR108 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor |
D | PHE196 | steric role |