2IBF

Human vinculin's head domain (Vh1, residues 1-258) in complex with two vinculin binding sites of Shigella flexneri's IpaA (residues 565-587)

Summary for 2IBF

• Entry DOI: 10.2210/pdb2ibf/pdb
• Related: 1RKC 1RKE 1SYQ 1YDI 2GWW 2HSQ
• Descriptor: Vinculin, Invasin ipaA (2 entities in total)
• Functional Keywords: cell adhesion, structural protein
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm, cytoskeleton: P18206; Secreted: P18010
• Total number of polymer chains: 3
• Total formula weight: 35530.80

Authors

Izard, T. (deposition date: 2006-09-11, release date: 2007-09-18, Last modification date: 2024-02-21)

• Primary citation: Nhieu, G.T.,Izard, T.; Vinculin binding in its closed conformation by a helix addition mechanism.; Embo J., 26:4588-4596, 2007; PubMed: 17932491; DOI: 10.1038/sj.emboj.7601863

Experimental method

X-RAY DIFFRACTION (3.2 Å)