2I7P

Crystal structure of human PANK3 in complex with AcCoA

Summary for 2I7P

Entry DOI	10.2210/pdb2i7p/pdb
Related	2I7N
Descriptor	Pantothenate kinase 3, ACETYL COENZYME *A (3 entities in total)
Functional Keywords	pank, structural genomics, structural genomics consortium, sgc, transferase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm (Probable): Q9H999
Total number of polymer chains	4
Total formula weight	163741.04
Authors	Hong, B.S.,Wang, L.,Shen, L.,Tempel, W.,Loppnau, P.,Finerty, P.,Arrowsmith, C.H.,Edwards, A.M.,Sundstrom, M.,Weigelt, J.,Bochkarev, A.,Park, H.W.,Structural Genomics Consortium (SGC) (deposition date: 2006-08-31, release date: 2006-12-26, Last modification date: 2024-02-21)
Primary citation	Hong, B.S.,Senisterra, G.,Rabeh, W.M.,Vedadi, M.,Leonardi, R.,Zhang, Y.M.,Rock, C.O.,Jackowski, S.,Park, H.W. Crystal structures of human pantothenate kinases. Insights into allosteric regulation and mutations linked to a neurodegeneration disorder. J.Biol.Chem., 282:27984-27993, 2007 Cited by PubMed: 17631502 DOI: 10.1074/jbc.M701915200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.05 Å)

Structure validation