2I5W

Structure of hOGG1 crosslinked to DNA sampling a normal G adjacent to an oxoG

Summary for 2I5W

• Entry DOI: 10.2210/pdb2i5w/pdb
• Related: 1EBM 1KO9 1YQK
• Descriptor: 5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*A)-3', 5'-D(P*CP*CP*AP*GP*(G42)P*TP*CP*TP*AP*C)-3', N-glycosylase/DNA lyase, ... (6 entities in total)
• Functional Keywords: disulfide crosslink, protein-dna complex, dna glycosylase, hydrolase, lyase-dna complex, lyase/dna
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus, nucleoplasm . Isoform 1A: Nucleus. Isoform 2A: Mitochondrion: O15527
• Total number of polymer chains: 3
• Total formula weight: 42362.82

Authors

Banerjee, A.,Verdine, G.L. (deposition date: 2006-08-26, release date: 2006-10-17, Last modification date: 2024-02-21)

• Primary citation: Banerjee, A.,Verdine, G.L.; A nucleobase lesion remodels the interaction of its normal neighbor in a DNA glycosylase complex.; Proc.Natl.Acad.Sci.Usa, 103:15020-15025, 2006; PubMed: 17015827; DOI: 10.1073/pnas.0603644103

Experimental method

X-RAY DIFFRACTION (2.6 Å)