2I3A
Crystal structure of N-Acetyl-gamma-Glutamyl-Phosphate Reductase (Rv1652) from Mycobacterium tuberculosis
Summary for 2I3A
Entry DOI | 10.2210/pdb2i3a/pdb |
Descriptor | N-acetyl-gamma-glutamyl-phosphate reductase, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL (3 entities in total) |
Functional Keywords | dimer interface beta sandwich, tetramer, rossmann fold, structural genomics, mycobacterium tuberculosis structural proteomics project, xmtb, oxidoreductase |
Biological source | Mycobacterium tuberculosis |
Cellular location | Cytoplasm (Probable): P63562 |
Total number of polymer chains | 4 |
Total formula weight | 146201.66 |
Authors | Cherney, L.T.,Cherney, M.M.,Garen, C.R.,Moraidin, F.,James, M.N.G.,Mycobacterium Tuberculosis Structural Proteomics Project (XMTB) (deposition date: 2006-08-17, release date: 2006-08-29, Last modification date: 2024-02-21) |
Primary citation | Cherney, L.T.,Cherney, M.M.,Garen, C.R.,Niu, C.,Moradian, F.,James, M.N.G. Crystal Structure of N-acetyl-gamma-glutamyl-phosphate Reductase from Mycobacterium tuberculosis in Complex with NADP(+). J.Mol.Biol., 367:1357-1369, 2007 Cited by PubMed: 17316682DOI: 10.1016/j.jmb.2007.01.033 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.15 Å) |
Structure validation
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