2I3A

Crystal structure of N-Acetyl-gamma-Glutamyl-Phosphate Reductase (Rv1652) from Mycobacterium tuberculosis

Summary for 2I3A

Entry DOI	10.2210/pdb2i3a/pdb
Descriptor	N-acetyl-gamma-glutamyl-phosphate reductase, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL (3 entities in total)
Functional Keywords	dimer interface beta sandwich, tetramer, rossmann fold, structural genomics, mycobacterium tuberculosis structural proteomics project, xmtb, oxidoreductase
Biological source	Mycobacterium tuberculosis
Cellular location	Cytoplasm (Probable): P63562
Total number of polymer chains	4
Total formula weight	146201.66
Authors	Cherney, L.T.,Cherney, M.M.,Garen, C.R.,Moraidin, F.,James, M.N.G.,Mycobacterium Tuberculosis Structural Proteomics Project (XMTB) (deposition date: 2006-08-17, release date: 2006-08-29, Last modification date: 2024-02-21)
Primary citation	Cherney, L.T.,Cherney, M.M.,Garen, C.R.,Niu, C.,Moradian, F.,James, M.N.G. Crystal Structure of N-acetyl-gamma-glutamyl-phosphate Reductase from Mycobacterium tuberculosis in Complex with NADP(+). J.Mol.Biol., 367:1357-1369, 2007 Cited by PubMed: 17316682 DOI: 10.1016/j.jmb.2007.01.033 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.15 Å)

Structure validation