2I1V
Crystal structure of PFKFB3 in complex with ADP and Fructose-2,6-bisphosphate
Summary for 2I1V
Entry DOI | 10.2210/pdb2i1v/pdb |
Related | 2AXN 2DWO 2DWP |
Descriptor | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3, 2,6-di-O-phosphono-beta-D-fructofuranose, 6-O-phosphono-beta-D-fructofuranose, ... (6 entities in total) |
Functional Keywords | ternary product complex, adp and f-2, 6-p2 in 2-kase, e-p and f-6-p in 2-pase, transferase, hydrolase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 60803.59 |
Authors | Kim, S.G.,El-Maghrabi, M.R.,Lee, Y.H. (deposition date: 2006-08-15, release date: 2007-07-03, Last modification date: 2023-10-25) |
Primary citation | Kim, S.G.,Cavalier, M.,El-Maghrabi, M.R.,Lee, Y.H. A Direct Substrate-Substrate Interaction Found in the Kinase Domain of the Bifunctional Enzyme, 6-Phosphofructo-2-kinase/Fructose-2,6-bisphosphatase J.Mol.Biol., 370:14-26, 2007 Cited by PubMed: 17499765DOI: 10.1016/j.jmb.2007.03.038 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
Download full validation report