2HRB

Crystal Structure of human Carbonyl Reductase 3, complexed with NADP+

Summary for 2HRB

DescriptorCarbonyl reductase [NADPH] 3, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, GLYCEROL, ... (4 entities in total)
Functional Keywordsretinol, dehydrogenase, peroxisome, structural genomics, short-chain dehydrogenase/reductase, structural genomics consortium, sgc, oxidoreductase
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm O75828
Total number of polymer chains1
Total molecular weight31558.5
Authors
Pilka, E.S.,Structural Genomics Consortium (SGC) (deposition date: 2006-07-20, release date: 2006-08-08, Last modification date: 2011-07-13)
Primary citation
Pilka, E.S.,Rojkova, A.,Kavanagh, K.L.,Niesen, F.,Sundstrom, M.,Arrowsmith, C.,Weigelt, J.,Edwards, A.,Oppermann, U.
Crystal Structure of human Carbonyl Reductase 3, complexed with NADP+
To be Published,
Experimental method
X-RAY DIFFRACTION (1.9 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.243402.6%3.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 2hrb
no rotation
Molmil generated image of 2hrb
rotated about x axis by 90°
Molmil generated image of 2hrb
rotated about y axis by 90°