Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000253 | molecular_function | 3-keto sterol reductase activity |
A | 0004090 | molecular_function | carbonyl reductase (NADPH) activity |
A | 0005515 | molecular_function | protein binding |
A | 0005615 | cellular_component | extracellular space |
A | 0005654 | cellular_component | nucleoplasm |
A | 0005737 | cellular_component | cytoplasm |
A | 0005829 | cellular_component | cytosol |
A | 0006805 | biological_process | xenobiotic metabolic process |
A | 0008753 | molecular_function | NADPH dehydrogenase (quinone) activity |
A | 0016491 | molecular_function | oxidoreductase activity |
A | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
A | 0042376 | biological_process | phylloquinone catabolic process |
A | 0050890 | biological_process | cognition |
A | 0070402 | molecular_function | NADPH binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 31 |
Details | BINDING SITE FOR RESIDUE NAP A 1001 |
Chain | Residue |
A | GLY12 |
A | ILE64 |
A | ASP65 |
A | ASN90 |
A | ALA91 |
A | ALA92 |
A | ILE138 |
A | SER139 |
A | TYR194 |
A | LYS198 |
A | PRO228 |
A | ASN14 |
A | GLY229 |
A | VAL231 |
A | ASP239 |
A | GOL2001 |
A | HOH2006 |
A | HOH2012 |
A | HOH2017 |
A | HOH2036 |
A | HOH2060 |
A | HOH2076 |
A | ARG15 |
A | HOH2139 |
A | HOH2169 |
A | GLY16 |
A | ILE17 |
A | ARG38 |
A | ARG42 |
A | LEU62 |
A | ASP63 |
site_id | AC2 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE GOL A 2001 |
Chain | Residue |
A | ALA92 |
A | VAL93 |
A | ALA94 |
A | TYR194 |
A | NAP1001 |
A | HOH2169 |
site_id | AC3 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE GOL A 2002 |
Chain | Residue |
A | HIS159 |
A | ARG206 |
A | ASN276 |
A | TRP277 |
A | HOH2130 |
A | HOH2135 |
A | HOH2219 |
site_id | AC4 |
Number of Residues | 10 |
Details | BINDING SITE FOR RESIDUE GOL A 2003 |
Chain | Residue |
A | ARG38 |
A | ASP39 |
A | VAL40 |
A | ALA41 |
A | ARG78 |
A | GLY82 |
A | PRO127 |
A | ILE128 |
A | HOH2030 |
A | HOH2108 |
Functional Information from PROSITE/UniProt
site_id | PS00061 |
Number of Residues | 29 |
Details | ADH_SHORT Short-chain dehydrogenases/reductases family signature. NevheregwpNspYGVSKLGVtVLSrILA |
Chain | Residue | Details |
A | ASN181-ALA209 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | VAL196 | |
site_id | SWS_FT_FI2 |
Number of Residues | 6 |
Details | BINDING: BINDING => ECO:0000269|Ref.13 |
Chain | Residue | Details |
A | GLY12 | |
A | VAL40 | |
A | ASP65 | |
A | ALA92 | |
A | VAL196 | |
A | ILE241 | |
site_id | SWS_FT_FI3 |
Number of Residues | 1 |
Details | BINDING: BINDING => ECO:0000250 |
Chain | Residue | Details |
A | GLN142 | |
Chain | Residue | Details |
A | ASP32 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 4 |
Details | Annotated By Reference To The Literature 1db3 |
Chain | Residue | Details |
A | GLN142 | |
A | SER140 | |
A | LYS198 | |
A | TYR194 | |
site_id | CSA2 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1db3 |
Chain | Residue | Details |
A | LYS198 | |
A | SER140 | |
A | TYR194 | |
site_id | CSA3 |
Number of Residues | 4 |
Details | Annotated By Reference To The Literature 1db3 |
Chain | Residue | Details |
A | ASN114 | |
A | LYS198 | |
A | SER140 | |
A | TYR194 | |
site_id | CSA4 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1db3 |
Chain | Residue | Details |
A | LYS198 | |
A | ASN191 | |
site_id | CSA5 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1db3 |
Chain | Residue | Details |
A | LYS198 | |
A | TYR194 | |