2HLE
Structural and biophysical characterization of the EPHB4-EPHRINB2 protein protein interaction and receptor specificity.
Summary for 2HLE
Entry DOI | 10.2210/pdb2hle/pdb |
Related | 1KGY 1NUK 2BBA |
Descriptor | Ephrin type-B receptor 4, Ephrin-B2 (3 entities in total) |
Functional Keywords | protein-protein interaction, receptor tryosine kinase, bi-directional cell signaling, transferase-transferase receptor complex, structural genomics, psi-2, protein structure initiative, accelerated technologies center for gene to 3d structure, atcg3d, transferase/transferase receptor |
Biological source | Homo sapiens (human) More |
Cellular location | Membrane; Single-pass type I membrane protein: P54760 P52799 |
Total number of polymer chains | 2 |
Total formula weight | 37141.29 |
Authors | Chrencik, J.E.,Brooun, A.,Kuhn, P.,Accelerated Technologies Center for Gene to 3D Structure (ATCG3D) (deposition date: 2006-07-06, release date: 2006-08-22, Last modification date: 2023-08-30) |
Primary citation | Chrencik, J.E.,Brooun, A.,Kraus, M.L.,Recht, M.I.,Kolatkar, A.R.,Han, G.W.,Seifert, J.M.,Widmer, H.,Auer, M.,Kuhn, P. Structural and Biophysical Characterization of the EphB4-EphrinB2 Protein-Protein Interaction and Receptor Specificity. J.Biol.Chem., 281:28185-28192, 2006 Cited by PubMed: 16867992DOI: 10.1074/jbc.M605766200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
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