2HFK
Pikromycin thioesterase in complex with product 10-deoxymethynolide
Summary for 2HFK
Entry DOI | 10.2210/pdb2hfk/pdb |
Related | 1MNA 2HFJ |
Descriptor | Type I polyketide synthase PikAIV, SULFATE ION, MAGNESIUM ION, ... (6 entities in total) |
Functional Keywords | alpha/beta hydrolase, thioesterase, hydrolase |
Biological source | Streptomyces venezuelae |
Total number of polymer chains | 2 |
Total formula weight | 68761.44 |
Authors | Akey, D.L.,Kittendorf, J.D.,Giraldes, J.W.,Fecik, R.A.,Sherman, D.H.,Smith, J.L. (deposition date: 2006-06-24, release date: 2006-09-19, Last modification date: 2023-08-30) |
Primary citation | Akey, D.L.,Kittendorf, J.D.,Giraldes, J.W.,Fecik, R.A.,Sherman, D.H.,Smith, J.L. Structural Basis for Macrolactonization by the Pikromycin Thioesterase NAT.CHEM.BIOL., 2:537-542, 2006 Cited by PubMed: 16969372DOI: 10.1038/nchembio824 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.79 Å) |
Structure validation
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