2HC0

Structure of HIV protease 6X mutant in complex with AB-2.

Summary for 2HC0

• Entry DOI: 10.2210/pdb2hc0/pdb
• Related: 1ZP8 2hb2 2hb4
• Descriptor: Protease, BROMIDE ION, [1-((1S,2R)-1-BENZYL-2-HYDROXY-3-{ISOBUTYL[(4-METHOXYPHENYL)SULFONYL]AMINO}PROPYL)-1H-1,2,3-TRIAZOL-4-YL]METHYL (1R,2R)-2-HYDROXY-2,3-DIHYDRO-1H-INDEN-1-YLCARBAMATE, ... (4 entities in total)
• Functional Keywords: hiv, protease, mutant, aspartyl, hydrolase
• Biological source: Human immunodeficiency virus 1
• Cellular location: Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P03367
• Total number of polymer chains: 2
• Total formula weight: 23122.05

Authors

Heaslet, H.,Brik, A.,Lin, Y.-C.,Elder, J.H.,Stout, C.D. (deposition date: 2006-06-14, release date: 2007-06-26, Last modification date: 2021-10-20)

• Primary citation: Heaslet, H.,Brik, A.,Lin, Y.-C.,Elder, J.H.,Stout, C.D.; Structure of HIV Protease 6X Mutant in complex with AB-2; To be Published,

Experimental method

X-RAY DIFFRACTION (1.3 Å)