Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0008233 | molecular_function | peptidase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0044174 | cellular_component | host cell endosome |
| A | 0055036 | cellular_component | virion membrane |
| A | 0072494 | cellular_component | host multivesicular body |
| B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| B | 0008233 | molecular_function | peptidase activity |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0044174 | cellular_component | host cell endosome |
| B | 0055036 | cellular_component | virion membrane |
| B | 0072494 | cellular_component | host multivesicular body |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE BR A 4001 |
| Chain | Residue |
| A | ARG1041 |
| A | THR1074 |
| A | ASN1088 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE BR B 4002 |
| Chain | Residue |
| B | ARG2141 |
| B | THR2174 |
| B | ASN2188 |
| B | HOH5230 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE BR B 4003 |
| Chain | Residue |
| A | ARG1008 |
| B | LEU2119 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE BR B 4004 |
| Chain | Residue |
| A | LEU1019 |
| B | LYS2107 |
| B | ARG2108 |
| site_id | AC5 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE BR B 4005 |
| site_id | AC6 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE BR A 4006 |
| site_id | AC7 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE BR A 4007 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE BR B 4008 |
| Chain | Residue |
| B | GLU2121 |
| B | HOH5247 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE BR B 4009 |
| Chain | Residue |
| B | ARG2141 |
| B | GLN2161 |
| site_id | BC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE BR A 4011 |
| Chain | Residue |
| A | GLY1048 |
| A | AB23500 |
| A | HOH5094 |
| A | HOH5156 |
| B | ILE2147 |
| B | GLY2148 |
| site_id | BC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE BR A 4012 |
| Chain | Residue |
| A | AB23500 |
| B | ARG2108 |
| B | HOH5243 |
| site_id | BC3 |
| Number of Residues | 35 |
| Details | BINDING SITE FOR RESIDUE AB2 A 3500 |
| Chain | Residue |
| A | ARG1008 |
| A | ASP1025 |
| A | GLY1027 |
| A | ALA1028 |
| A | ASP1029 |
| A | ASP1030 |
| A | ILE1047 |
| A | GLY1048 |
| A | GLY1049 |
| A | ILE1050 |
| A | PRO1081 |
| A | ILE1084 |
| A | BR4011 |
| A | BR4012 |
| A | HOH5066 |
| A | HOH5094 |
| A | HOH5098 |
| A | HOH5122 |
| A | HOH5281 |
| B | ARG2108 |
| B | ASP2125 |
| B | GLY2127 |
| B | ALA2128 |
| B | ASP2129 |
| B | ASP2130 |
| B | ILE2147 |
| B | GLY2148 |
| B | GLY2149 |
| B | ILE2150 |
| B | THR2180 |
| B | PRO2181 |
| B | ALA2182 |
| B | ILE2184 |
| B | HOH5002 |
| B | HOH5038 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ALIDTGADDTVL |
| Chain | Residue | Details |
| A | ALA1022-LEU1033 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | THR1026 | |
| B | THR2126 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | SITE: Cleavage; by viral protease => ECO:0000250 |
| Chain | Residue | Details |
| A | PRO1001 | |
| B | PRO2101 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1a30 |
| Chain | Residue | Details |
| A | THR1026 | |
| A | ASP1025 | |
| B | ASP2125 | |
| B | THR2126 | |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a30 |
| Chain | Residue | Details |
| A | ASP1025 | |
| B | ASP2125 | |
