2HB2

Structure of HIV protease 6X mutant in apo form

Summary for 2HB2

Entry DOI	10.2210/pdb2hb2/pdb
Related	2AZC 2hb4 2hc0
Descriptor	Protease (2 entities in total)
Functional Keywords	hiv, protease, retrovirus, aspartyl, hydrolase
Biological source	Human immunodeficiency virus 1
Cellular location	Gag-Pol polyprotein: Host cell membrane ; Lipid-anchor. Matrix protein p17: Virion membrane; Lipid- anchor . Capsid protein p24: Virion . Nucleocapsid protein p7: Virion . Reverse transcriptase/ribonuclease H: Virion . Integrase: Virion : P03367
Total number of polymer chains	1
Total formula weight	10749.71
Authors	Heaslet, H.,Tam, K.,Elder, J.H.,Stout, C.D. (deposition date: 2006-06-13, release date: 2007-06-26, Last modification date: 2024-02-14)
Primary citation	Heaslet, H.,Rosenfeld, R.,Giffin, M.,Lin, Y.C.,Tam, K.,Torbett, B.E.,Elder, J.H.,McRee, D.E.,Stout, C.D. Conformational flexibility in the flap domains of ligand-free HIV protease. Acta Crystallogr.,Sect.D, 63:866-875, 2007 Cited by PubMed: 17642513 DOI: 10.1107/S0907444907029125 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation